Discovering, Developing & Chemically Optimising Nucleic Acid Therapies for Precise Delivery to Undruggable CNS Targets
Europe’s oligonucleotide landscape is entering a pivotal growth phase. With the €21M launch of Aerska and major collaborations such as Novartis and SciNeuro, Lundbeck and Contera, and Secarna and Vect-Horus, European biopharma companies are rapidly advancing RNA-targeted approaches to address previously undruggable CNS diseases.
In response to this momentum, the inaugural Oligonucleotides for CNS Summit Europe will unite 60+ senior industry leaders for the first European forum dedicated exclusively to CNS-focused oligonucleotide therapeutics.
The summit delivers three days of highly technical, data-driven discussions addressing the challenges unique to CNS development, with insights into next-generation BBB delivery strategies beyond TfR1, advanced in vivo and iPSC models, novel chemistry and conjugation approaches, and translational strategies bridging preclinical data to clinical and regulatory success.
Now is the moment to connect, collaborate and shape the next wave of RNA-based CNS innovation as the field accelerates globally.
Testimonials from the 5th Oligonucleotide for CNS US Summit
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Speaker Spotlight!
We're delighted to announce that Farzaneh Salem, Associate Director, GSK will be presenting at the summit, speaking on 'Predictive Power of PBPK Models to Guide CNS Oligonucleotide PK & Cellular Targeting'.
The session will cover the development and validation of PBPK models for predicting in vivo CNS exposure, distribution, and cellular engagement. As well as characterising cell-type–specific targeting in the CNS through consideration of biological barriers, cellular diversity, and molecular design.
Want to see who else is speaking and what’s on the agenda? Checkout the Event Guide here.
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